Molecular Basis of Angiogenesis in Ovarian Cancer

نویسندگان

  • L. Pirtea
  • D. Grigoras
  • R. Ilina
  • M. Raica
چکیده

Epithelial ovarian cancer (EOC) is the most common malignancy of the female genital tract in Western countries: 1–2% of all women develop EOC at some time during their lives. Most women with EOC present with peritoneal spread, the principal cause of morbidity and mortality. Owing to the paucity of symptoms and their insidious onset, most patients present with advanced disease, and five year survival rates are around 20%. At present, EOC has by far the worst prognosis of all gynecological cancers and is responsible for half the deaths caused by female genital tract malignancy. The conventional tehrapeutic protocols have so far disappointing results. There is a need for new

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تاریخ انتشار 2012